spfpХранение и переработка сельхозсырьяStorage and Processing of Farm Products2072-96692658-767XРОСБИОТЕХ10.36107/spfp.2022.305spfp-305Research ArticleИССЛЕДОВАНИЕ СВОЙСТВ ВЕЩЕСТВ И ПРОДУКЦИИ АПКRESEARCH ON TRAITS OF SUBSTANCES AND AGRIBUSINESS PRODUCTSАнтиоксидантная активность цетрарии исландской (Cetraria islandica (L.) Ach.), используемой в качестве биологически активной добавкиAntioxidant activity of Icelandic Cetraria (Cetraria islandica (L.) Ach.), used as a dietary supplementhttps://orcid.org/0000-0002-1601-7371КотоваТатьяна ВячеславовнаKotovaTat'yana V.

кафедра фармацевтической и общей химии, профессор

СПИН-код:  2073-0189

t_kotova@inbox.ruhttps://orcid.org/0000-0003-4874-3420МальцеваЕлена МихайловнаMaltsevaElena M.

кафедра фармацевтической и общей химии, заведующий

СПИН-код: 1687-9895

elen-malceva@yandex.ruhttps://orcid.org/0000-0002-8084-2536ВальнюковаАнастасия СергеевнаValnyukovaAnastasia S.

кафедра фармацевтической и общей химии, доцент

СПИН-код: 4987-5386

nastya711@bk.ruBhatiaNaveenBhatiaNaveenbhatianaveen17@gmail.comhttps://orcid.org/0000-0001-6146-0965ТихоноваОльга ЮрьевнаTikhonovaOlga Yu.

преподаватель

СПИН-код: 7347-0037

olga_tixonova_76@mail.ruКемеровский государственный медицинский университетРоссияKemerovo State Medical UniversityRussian FederationГоспиталь и медицинский исследовательский центр PD HindujИндияP.D. Hinduja Hinduja Hospital & Medical Research CentreIndiaФГБОУ ВО «Кемеровский государственный медицинский университет»РоссияKemerovo State Medical UniversityRussian Federation20222607202202107119Copyright © Котова Т.В., Мальцева Е.М., Вальнюкова А.С., Bhatia N., Тихонова О.Ю., 20222022Котова Т.В., Мальцева Е.М., Вальнюкова А.С., Bhatia N., Тихонова О.Ю.Kotova T.V., Maltseva E.M., Valnyukova A.S., Bhatia N., Tikhonova O.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.spfp-mgupp.ru/jour/article/view/305

Предпосылки проведения исследования: Метаболиты рода Cetraria лишайников семейства Parmeliaceae обладают антибактериальной, противогрибковой, про-тивовирусной, иммуномодулирующей, противоопухолевой и антиоксидантной активностью. Заполняемый пробел в существующем знании и цель исследования: Антиокси-дантная активность (АОА) извлечений, полученных с помощью экстрагентов с различной полярностью, зависит не только от содержания соединений феноль-ного характера, но и от веществ нефенольной природы и является результатом синергетических и антагонистических эффектов взаимодействия нескольких классов биологически активных соединений. Слоевища цетрарии исландской могут служить перспективным источником природных биологически активных соединений, обладающих умеренным антиоксидантным потенциалом.Материалы и методы исследования: В работе проанализированы результаты изучения антиоксидантной активности (АОА) извлечений, полученных экстра-гентами различной полярности. АОА определяли с использованием спектрофо-тометрических методов in vitro. Результаты и их применение: Ацетоновые и спиртовые извлечения, получен-ные из сырья, и водные отвары обладали умеренной антиоксидантной активно-стью, в сравнении с известными пищевыми антиоксидантами аскорбиновой кислотой. Наибольшей способностью в отношении ингибирования свободного радикала 2,2-дифенил-1-пикрилгидразилом (DPPH) обладает спиртовое извле-чение. Самое высокое содержание фенольных соединений выявлено в водном извлечении слоевищ цетрарии исландской. А самую высокую железохелатиру-ющую активность проявляет ацетоновое извлечение. 

Research background: Metabolites of the genus Cetraria of lichens of the Parmeliace-ae family have antibacterial, antifungal, antiviral, immunomodulatory, antitumor, and antioxidant activity. Gap to be filled in existing knowledge and purpose of the study:The paper analyzes the results of studying the antioxidant activity (AOA) of extracts obtained with ex-tractants of different polarity. Materials and methods of research: AOA was determined using in vitro spectropho-tometric methods. Acetone and alcohol extracts obtained from raw materials and wa-ter decoctions had a moderate antioxidant activity, in comparison with the known food antioxidants ascorbic acid. Results and their application: Alcohol extract has the highest ability to inhibit the DPPH radical. The highest content of phenolic compounds was found in the aqueous extract of the thallus of the Icelandic cetraria. And the highest iron chelating activity is shown by acetone extract. The AOA of extracts obtained using extractants with dif-ferent polarity depends not only on the content of phenolic compounds, but also on non-phenolic substances and is the result of synergistic and antagonistic effects of the interaction of several classes of biologically active compounds. Thallus of Icelandic cetraria can serve as a promising source of natural biologically active compounds with a moderate antioxidant potential.

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The authors declare that there are no conflicts of interest present.