spfpХранение и переработка сельхозсырьяStorage and Processing of Farm Products2072-96692658-767XРОСБИОТЕХ10.36107/spfp.2025.2.656spfp-656Research ArticleБИОТЕХНОЛОГИЧЕСКИЕ И МИКРОБИОЛОГИЧЕСКИЕ АСПЕКТЫBIOTECHNOLOGICAL AND MICROBIOLOGICAL ASPECTSФункциональные свойства гидролизатов белков рапса: систематический обзор биологической активности и областей примененияFunctional Properties of Rapeseed Protein Hydrolysates: A Systematic Review of Their Biological Activity and Applicationshttps://orcid.org/0000-0003-4298-0927ЧернухаИрина МихайловнаChernukhaIrina M.

Главный научный сотрудник ФГБНУ «ФНЦ пищевых систем им. В.М. Горбатова» РАН, Экспериментальная клиника – лаборатория биологически активных веществ животного происхождения, 

SPIN-код: 3423-3754

Chief Research Scientist, V. M. Gorbatov Federal Research Center for Food Systems, Russian Academy of Sciences, SPIN: 3423-3754

imcher@inbox.ruhttps://orcid.org/0000-0003-4863-9834ТихоновСергей ЛеонидовичTikhonovSergey L.

Профессор, Зав. кафедрой пищевой инженерии аграрного производства, ФГБОУ ВО «Уральский государственный аграрный университет», SPIN-код: 4649-8616

Head of the Department of Food Engineering for Agricultural Production, Ural State Agrarian University, SPIN: 4649-8616

tihonov75@bk.ruhttps://orcid.org/0000-0002-3842-1391ДегтяревИван АлександровичDegtyarevIvan A.

Аспирант кафедры биотехнологии и биоорганического синтеза ФГБОУ ВО Российский биотехнологический университет (РОСБИОТЕХ),

SPIN-код: 9200-9527

 

Graduate student, Department of Biotechnology and Bioorganic Synthesis, Russian Biotechnological University, SPIN: 9200-9527

iadegtyarev@mail.ruhttps://orcid.org/0000-0003-2478-1705ФоменкоИван АндреевичFomenkoIvan A.

Доцент кафедры биотехнологии и биоорганического синтеза ФГБОУ ВО Российский биотехнологический университет (РОСБИОТЕХ),

SPIN-код: 5861-2838

Docent, Department of Biotechnology and Bioorganic Synthesis, Russian Biotechnological University (ROSBIOTECH), SPIN: 5861-2838

iv.fomenko@mail.ruhttps://orcid.org/0009-0004-0985-9505ДетинкинИлья АлександровичDetinkinIlya A.

Магистр кафедры биотехнологии и биоорганического синтеза ФГБОУ ВО Российский биотехнологический университет (РОСБИОТЕХ),

SPIN-код: 4596-4802

Master’s student, Department of Biotechnology and Bioorganic Synthesis, Russian Biotechnological University (ROSBIOTECH), SPIN: 4596-4802

detinkin02@gmail.comФГБНУ «ФНЦ пищевых систем им. В.М. Горбатова» РАНРоссияFederal State Budgetary Scientific Institution «V.M. Gorbatov Federal Research Center for Food Systems» of the Russian Academy of SciencesRussian FederationУральский государственный аграрный университетРоссияUral State Agrarian UniversityRussian FederationРоссийский биотехнологический университетРоссияRussian Biotechnological University (ROSBIOTECH)Russian FederationРоссийский биотехнологический университетРоссияRussian Biotechnological UniversityRussian Federation202530062025332109141Copyright © Чернуха И.М., Тихонов С.Л., Дегтярев И.А., Фоменко И.А., Детинкин И.А., 20252025Чернуха И.М., Тихонов С.Л., Дегтярев И.А., Фоменко И.А., Детинкин И.А.Chernukha I.M., Tikhonov S.L., Degtyarev I.A., Fomenko I.A., Detinkin I.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.spfp-mgupp.ru/jour/article/view/656Введение

Введение: Растительные масла широко применяются в различных отраслях промышленности, что стимулирует рост производства масличных культур. Особенно быстро расширяются посевы рапса, по которому Россия входит в десятку мировых лидеров. При этом побочные продукты переработки рапса (жмыхи и шроты), содержащие более 40% белка, остаются недооцененным ресурсом для получения белковых препаратов. Исследование гидролизатов рапсового белка, содержащих биологически активные пептиды, представляет особый интерес для пищевой, кормовой и фармацевтической промышленности.

Цель

Цель: Провести обобщение и систематизацию актуальных научных данных о гидролизатах рапсового белка, охватывая технологии их получения, выявленные биологические свойства и возможные области применения. В рамках анализа отдельный акцент сделан на исследованиях, описывающих пептиды с антиоксидантной, антимикробной, антигипертензивной, DPP-IV-ингибирующей и противоопухолевой активностью. 

Материалы и методы

Материалы и методы: В основу систематического обзора положен анализ научных публикаций, опубликованных в период с 2014 по 2025 год в рецензируемых журналах, индексируемых в международных и национальных базах данных. Источники были отобраны с использованием поисковых систем Google Scholar, PubMed, ScienceDirect, SpringerLink и РИНЦ. Критерии включения охватывали тематическую релевантность, наличие научной новизны, а также публикацию в изданиях, входящих в признанные индексы научного цитирования. В обзор включены как экспериментальные исследования, выполненные in vitro и in vivo, так и работы, основанные на методах in silico моделирования. Процесс идентификации, отбора, систематизации и анализа источников представлен с использованием диаграммы PRISMA.

Результаты

Результаты: Установлено, что гидролизаты рапсового белка могут служить ценными функциональными ингредиентами в пищевых продуктах, кормах для аквакультуры и источниками биоактивных соединений. Обсуждается влияние методов гидролиза на их функционально-технологические свойства, а также потенциал замены традиционных белковых компонентов. Выделены перспективные направления дальнейших исследований, включая применение новых ферментных препаратов и биоинформационных подходов для идентификации биологически активных пептидов.

Выводы

Выводы: Гидролизаты рапсового белка обладают значительным потенциалом для использования в различных отраслях промышленности. Дальнейшие исследования должны быть направлены на оптимизацию методов их получения, углубленное изучение механизмов биологической активности и расширение областей практического применения. Разработка новых технологий переработки рапсового белка может способствовать созданию инновационных продуктов с улучшенными функциональными свойствами.

Introduction

Introduction: Vegetable oils are widely used in various industries, which stimulates the growth of oilseed production. Rapeseed crops are expanding especially rapidly, for which Russia is one of the ten world leaders. At the same time, by-products of rapeseed processing (oilcakes and meal) containing more than 40% protein remain an underestimated resource for obtaining protein preparations. The study of rapeseed protein hydrolysates containing biologically active peptides is of particular interest to the food, feed, and pharmaceutical industries.

Purpose

Purpose: To summarize and systematize current scientific data on rapeseed protein hydrolysates, including production methods, identified biological activities, and potential areas of application. The analysis places particular emphasis on studies reporting peptides with antioxidant, antimicrobial, antihypertensive, DPP-IV-inhibitory, and anticancer activities. 

Materials and Methods

Materials and Methods: The systematic review is based on an analysis of scientific publications published between 2014 and 2025 in peer-reviewed journals indexed in international and national databases. Sources were selected using search engines such as Google Scholar, PubMed, ScienceDirect, SpringerLink, and the Russian Science Citation Index (RSCI). The inclusion criteria comprised thematic relevance, scientific novelty, and publication in journals recognized by established citation indices. The review incorporates both experimental studies conducted in vitro and in vivo, as well as research based on in silico modeling methods. The process of source identification, selection, systematization, and analysis is presented using a PRISMA flow diagram.

Results

Results: It has been established that rapeseed protein hydrolysates can serve as valuable functional ingredients in food products, aquaculture feeds and sources of bioactive compounds. The influence of hydrolysis methods on their functional and technological properties, as well as the potential for replacing traditional protein components, is discussed. Promising areas of further research have been identified, including the use of new enzyme preparations and bioinformatics approaches for the identification of biologically active peptides.

Conclusion

Conclusion: Rapeseed protein hydrolysates have significant potential for use in various industries. Further research should be aimed at optimizing the methods of their preparation, in-depth study of the mechanisms of biological activity and expanding the areas of practical application. The development of new rapeseed protein processing technologies can contribute to the creation of innovative products with improved functional properties.

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The authors declare that there are no conflicts of interest present.