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Antioxidant activity of Icelandic Cetraria (Cetraria islandica (L.) Ach.), used as a dietary supplement

https://doi.org/10.36107/spfp.2022.305

Abstract

Research background: Metabolites of the genus Cetraria of lichens of the Parmeliace-ae family have antibacterial, antifungal, antiviral, immunomodulatory, antitumor, and antioxidant activity. 
Gap to be filled in existing knowledge and purpose of the study:The paper analyzes the results of studying the antioxidant activity (AOA) of extracts obtained with ex-tractants of different polarity. 
Materials and methods of research: AOA was determined using in vitro spectropho-tometric methods. Acetone and alcohol extracts obtained from raw materials and wa-ter decoctions had a moderate antioxidant activity, in comparison with the known food antioxidants ascorbic acid. 
Results and their application: Alcohol extract has the highest ability to inhibit the DPPH radical. The highest content of phenolic compounds was found in the aqueous extract of the thallus of the Icelandic cetraria. And the highest iron chelating activity is shown by acetone extract. The AOA of extracts obtained using extractants with dif-ferent polarity depends not only on the content of phenolic compounds, but also on non-phenolic substances and is the result of synergistic and antagonistic effects of the interaction of several classes of biologically active compounds. Thallus of Icelandic cetraria can serve as a promising source of natural biologically active compounds with a moderate antioxidant potential.

About the Authors

Tat'yana V. Kotova
Kemerovo State Medical University
Russian Federation


Elena M. Maltseva
Kemerovo State Medical University
Russian Federation


Anastasia S. Valnyukova
Kemerovo State Medical University
Russian Federation


Naveen Bhatia
P.D. Hinduja Hinduja Hospital & Medical Research Centre
India


Olga Yu. Tikhonova
Kemerovo State Medical University
Russian Federation


References

1. Pereverzeva E. V., Filippova S. N. Nutrition of modern man: the path of development or degradation? // Vestnik RMAT. 2015. No. 4. P. 116-130.

2. Kershengolts B. M., Zhuravskaya A. N., Shashurin M. M. Biologically active additives based on lichens: new biotechnologies, composition, applications // New and non-traditional plants and prospects for their use. 2016. No. 12. S. 481-486.

3. Meli M. A., Desideri D., Cantaluppi C., Ceccotto F., Feduzi L., & Roselli C. Elemental and radiological characterization of commercial Cetraria islandica (L.) // Acharius pharmaceutical and food supplementation products. Science of the Total Environment. 2018. рр. 613-614.

4. Xu M., Heidmarsson S., Thorsteinsdottir M., Kreuzer M., Hawkins J., Omarsdottir S., & Olafsdottir E. S. Authentication of Iceland Moss (Cetraria is-landic) by UPLC-QtoF-MS chemical profiling and DNA barcoding // Food Chem-istry. 2018. рр. 245, 989-996.

5. Turk A. O., Yilmaz M., Kivanc M., Turk H. The antimicrobial activity of extracts of the lichen Cetraria Aculeata and its prottolichesterinic acid constituent // Z. Naturforsch. 2003. 58 (11-12). рр. 850-854.

6. Ingólfsdóttir K. Bioactive Compounds From Iceland Moss. Bioactive Carbohydrate Polymers // Kluwer Academic Publishers, Dordrecht. 2000. pp. 25-36.

7. Freysdottir J., Omarsdottir S., Ingolfsdottir K., Vikingsson A., Olafsdot-tir

8. E. S. In vitro and in vivo immunomodulating effects of traditionally prepared ex-tract and purified compoumds from Cetraria islandica // Int. Immunopharmacol. 2008. 8/3, 423-430.

9. Stubler D., Buchenauer H. Antiviral activity of the glucan lichenan. Studies on the modes of action // J. Phytopathol. 1996. рр. 144, 45-52.

10. Haralsdottir S., Guolaugsdottir E., Ingólfsdóttir K. Antiproliferative ef-fects of lichen-derived lipoxygenase inhibitors on twelve human cancer cell lines of different tissue origin in vitro // Planta Med. 2004. 70 (11). рр. 109-1100.

11. Kotan E., Alpsoy L., Anar M. Protective role of methanolextract of Ce-traria islandica (L.) against oxidative stress and genotoxic effects of AFB, in hu-man lymphocites in vitro // Toxicol. Ind. Health. 2011. 27 (7). рр. 599-605.

12. Vasudeo P., Zambare & Lew P. Christopher. Biopharmaceutical poten-tial of lichens // Pharmaceutical Biology. 2012. 50:6. рp. 778-798. DOI: 10.3109/13880209.2011.633089.

13. Bazhenova B. A., Badmaeva T. M., Rinchinova M. Zh., Vasilyeva A. B., Gyndykova D. B. Study of the antioxidant activity of Icelandic cetraria decoc-tion // Technique and food technology: Science. Education. Achievements. Innovation. 2014. S. 81-86.

14. Zhang Y. J., Gan R. Y., Li S., Zhou Y., Li A. N., Xu D. P. et al. Anti-oxidant phytochemicals for the prevention and treatment of chronic diseases // Molecules 2015 Dec.; 20(12):21138e56.

15. Egorova N. O., Maltseva E. M., Egorova I. N., Egorova O. N., Seriko-va N. B. Antimicrobial and antiradical activity of dry extracts of the herb San-qisorba officinalis L. // Modern problems of science and education. 2018. No. 3. P. 14.

16. Zhang W. M., Lin Han B. L., Zhang H. D. Antioxidant activities of ex-tracts from Areca (Areca catectu L.) flower, husk and seed // Electron J Environ Agric Food Chem. 2009. 8. рр. 740-748.

17. Kosanić M., Ranković B., Vukojević J. Antioxidant properties of some lichen species // J Food Sci Technol. 2011. 48(5). рр. 584-590. DOI: 10.1007/s13197-010-0174-2.

18. White P. A., Oliveira R. C., Oliveira A. P., et al. Antioxidant activity and mechanisms of action of natural compounds isolated from lichens // A sys-tematic re-view. Molecules. 2014. 19(9): 14496-14527. Published 2014 Sep. 12. DOI: 10.3390/molecules190914496.

19. Ghazzawi H. A., Al-Sayyed H. F., Al-Kurd R. A., Mwalla M. M., Ara-fat T. A., & AbdelQader S. M. Effect of different extraction solvents on the anti-oxidant content and capacity of nine seasonal fruits // Clinical Nutrition Open Science. 2021. рр. 38, 33-42.

20. Zverev Ya. F. Flavonoids through the eyes of a pharmacologist. Anti-oxidant and anti-inflammatory activity // Reviews of clinical pharmacology and drug therapy. 2017. V. 15. No. 4. S. 5-13.

21. Procházková D., Boušová I., Wilhelmová N. Antioxidant and prooxi-dant properties of flavonoids // Fitoterapia. 2011. N 82(4). рр. 513-23.

22. Maltseva E. M., Egorova N. O., Egorova I. V., Mukhamadiyarov R. A. Antioxidant and antiradical activity in vitro of extracts of the herb Sanguisorba officinalis L., collected in different phases of development // Medicine in Kuzbass. 2017. V. 16. No. 2. S. 32-38.

23. Madhavi D. L., Deshpande S. S., Salunkhe D. K. Food antioxidants: Technological: Toxicological and health perspectives. – CRC Press, 1995.

24. Sasikumar J. M., Mathew G. M., Teepica P. D. D. Comparative studies on antioxidant activity of methanol extract and flavonoid fraction of Nyctanthes arbortristis leaves // EJEAFChe. 2010. Т. 9. №. 1. С. 227-33.

25. White P. A., Oliveira R. C., Oliveira A. P., et al. Antioxidant activity and mechanisms of action of natural compounds isolated from lichens: a system-atic review. Molecules. 2014. 19(9): 14496-14527. DOI: 10.3390/molecules190914496

26. Odabasoglu F., Aslan A., Cakir A., Suleyman H., Karagoz Y., Halici M., Bayir Y. Comparison of antioxidant activity and phenolic content of three lichen species // Phytother Res. 2004. Nov. 18(11): 938-41. DOI: 10.1002/ptr.1488.

27. Stojanovic G., Stojanovic I., Stankov-Jovanovic V., Mitic V., Kostic D. Reducing power and radical scavenging activity of four Parmeliaceae species // Central European Journal of Biology. 2010. 5(6). рр. 808-813. DOI: 10.2478/s11535-010-0090-5.

28. Lopes T. I., Coelho R. G., Yoshida N. C., Honda N. K. Radical-scavenging activity of orsellinates // Chem Pharm Bull (Tokyo). 2008. Nov. 56(11). рр. 1551-1554. DOI: 10.1248/cpb.56.1551.

29. Giordani P., Minganti V., Brignole D., Malaspina P., Cornara, L., & Drava G. A test study on the lichen Cetraria islandica // Chemosphere. 2017. 181. рр. 778-785.

30. Agnieszka Galanty, Michal Wegrzyn, Paulina Wietrzyk-Pelka, Maria Folta, Miroslaw Krosniak, Irma Podolak, Pawel Zagrodzki. Quantitative varia-tions of usnic acid and selected elements in terricolous lichen Cladonia mitis Sandst., with respect to different environmental factors – A chemometric ap-proach // Phytochemistry. 2021. Volume 192. 112948.

31. Zhao Y., Wang M., Xu B. A comprehensive review on secondary me-tabolites and health-promoting effects of edible lichen // J. Funct. Foods. 2020. pp. 104283.

32. Schmitt I., Lumbsch H. T. Molecular phylogeny of the Pertusariaceae supports secondary chemistry as an important systematic character set in lichen-forming ascomycetes // Mol Phylogenet Evol. 2004. Oct. 33(1). рр. 43-55. DOI: 10.1016/j.ympev.2004.04.014.

33. Xu M., Heidmarsson S., Olafsdottir E. S., Buonfiglio R., Kogej T., Omarsdottir S. Secondary metabolites from cetrarioid lichens: Chemotaxonomy, biological activities and pharmaceutical potential // Phytomedicine. 2016. May 15; 23(5): 441-59. DOI: 10.1016/j.phymed.2016.02.012.

34. Brewer M. S. Natural antioxidants: sources, compounds, mechanisms of action, and potential applications // Comprehensive reviews in food science and food safety. 2011. Т. 10. №. 4. С. 221-247.

35. Schinkovitz A., Le Pogam P., Derbré S., Roy-Vessieres E., Blanchard P., Thirumaran S. L., Breard D., Aumond M. C., Zehl M., Urban E, Kaur A., et al. Secondary metabolites from lichen as potent inhibitors of advanced glycation end products and vasodilative agents // Fitoterapia. 2018. Vol. 131. рр. 182-188, DOI: 10.1016/j.fitote.2018.10.015.

36. European Pharmacopoeia. 8th Edition.Vol. 1. Supplement 8.0 // EDQM, 2014-2015. рр. 1275-1275.

37. Meli M. A., Desideri D., Cantaluppi C., Ceccotto F., Feduzi L., Roselli C. Elemental and radiological characterization of commercial Cetraria islandica (L.) Acharius pharmaceutical and food supplementation products // Science of The Total Environment. 2018. 613-614. pp. 1566-1572.

38. Ullah S., Khalil A. A., Shaukat F. Sources extraction and biomedical properties of polysaccharides // Foods. 2019. 8 (8). pp. 304.

39. Swati S. Mishra, Sudhanshu S. Behera, Latiful Bari, Sandeep K. Pan-da, Steve C. Z. Desobgo Microbial bioprocessing of health promoting food sup-plements // Applied Biotechnology Reviews. 2021. pp. 113-141.

40. Dar T. U. H., Dar S. A., Islam S. U., Mangral Z. A., Dar R., Singh B. P., Haque S. Lichens as a repository of bioactive compounds: an open window for green therapy against diverse cancers // Seminars in Cancer Biolog., 2021.


Review

For citations:


Kotova T.V., Maltseva E.M., Valnyukova A.S., Bhatia N., Tikhonova O.Yu. Antioxidant activity of Icelandic Cetraria (Cetraria islandica (L.) Ach.), used as a dietary supplement. Storage and Processing of Farm Products. 2022;(2). (In Russ.) https://doi.org/10.36107/spfp.2022.305

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