Investigation of the phytochemical platform of a number of plants with antidiabetic effect

Abstract

The article considers one of the aspects of the problem - the treatment and prevention of diabetes mellitus using a phytocomposition compiled on the basis of plants of the domestic flora. The components of the composition are plants growing in Tajikistan and having a reliable raw material base. And since interest in the treatment of diabetes mellitus has recently grown due to the appearance of coronavirus infection and its consequences, the relevance of this fragment is clearly expressed. And especially attractive is the fact that it is the natural composition that is being investigated for this purpose, which is also distinguished by its novelty. The proposed complex in the form of dry extracts showed hypoglycemic activity. In this regard, phytochemical studies were performed on the polyphenol complex and vitamin C, which showed a positive result. These studies were carried out using a spectrophotometer. Licorice was chosen as the dominant pharmacological indicator: at the same time, a triterpene complex with a predominance of glycyrrhizic acid was determined, affecting the antidiabetic effect, which was tested and proved, in turn, on a model of diabetes mellitus. It turned out that the content of glycyrrhizic acid in the dry extract is 6,197%. Thus, the presence in the studied phytocomposition consisting of dry extracts of licorice, galega, linden, nettle, mint, rosehip, polyphenolic complex and vitamin C was confirmed, and a significant role in this complex of licorice was noted.